DUSP22 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14065-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14065-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14065-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14065-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DUSP22
Background:
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human DUSP22
Purification method:
Affinity purification
Target Synonym:
Dual specificity protein phosphatase 22;DUS22;Dusp22;JNK stimulatory phosphatase 1;JNK-stimulatory phosphatase-1;JSP 1;JSP-1;JSP1;LMW DSP2;LMW-DSP2;Low molecular weight dual specificity phosphatase 2;MAP kinase phosphatase x;Mitogen activated protein kinase phosphatase x;Mitogen-activated protein kinase phosphatase x;MKP-x;MKPX
UNIProt ID:
Q9NRW4