DRD4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12360-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12360-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12360-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12360-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DRD4
Background:
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
48kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150
Immunogen:
Synthetic peptide of human DRD4
Purification method:
Affinity purification
Target Synonym:
D(2C) dopamine receptor;D(4) dopamine receptor (D(2C) dopamine receptor).;D(4) dopamine receptor;D4 dopamine receptor;D4DR;Dopamine D4 receptor;DRD 4;Drd4;DRD4
UNIProt ID:
P21917