DNMT3A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14623-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14623-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14623-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14623-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DNMT3A
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human DNMT3A
Purification method:
Affinity purification
Target Synonym:
DNA (cytosine 5) methyltransferase 3 alpha;DNA (cytosine 5) methyltransferase 3A;DNA (cytosine-5)-methyltransferase 3A;DNA cytosine methyltransferase 3A2;DNA methyltransferase 3 alpha;DNA methyltransferase 3a;DNA methyltransferase HsaIIIA;DNA MTase HsaIIIA;DNM3A;DNMT 3a;DNMT;Dnmt3a;DNMT3A2;M.HsaIIIA;MCMT;OTTHUMP00000201149;TBRS
UNIProt ID:
Q9Y6K1