DIABLO Polyclonal Antibody
Code | Size | Price |
---|
E-AB-10598-20uL | 20uL | £125.00 |
Quantity:
E-AB-10598-60uL | 60uL | £172.00 |
Quantity:
E-AB-10598-120uL | 120uL | £237.00 |
Quantity:
E-AB-10598-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
DIABLO
Background:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
27kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human DIABLO
Purification method:
Affinity purification
Target Synonym:
0610041G12Rik;DBLOH;DBOH;DFNA64;diablo;Diablo homolog (Drosophila);Diablo homolog;Diablo homolog mitochondrial;Diablo IAP binding mitochondrial protein;Diablo like protein;DIABLO S;Direct IAP binding protein with low pI;Direct IAP-binding protein with low pI;FLJ10537;FLJ25049;mitochondrial;Mitochondrial Smac protein;Second mitochondria derived activator of caspase;Second mitochondria-derived activator of caspase;SMAC 3;Smac;Smac protein;SMAC3
UNIProt ID:
Q9NR28