DHCR24 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15380-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15380-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15380-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15380-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DHCR24
Background:
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150
Immunogen:
Recombinant protein of human DHCR24
Purification method:
Affinity purification
Target Synonym:
24 dehydrocholesterol reductase;24-dehydrocholesterol reductase;3 beta hydroxysterol delta 24 reductase;3-beta-hydroxysterol delta-24-reductase;DCE;Delta(24)-sterol reductase;Desmosterol to cholesterol enzyme;DHC24;Dhcr24;Diminuto dwarf1 homolog;Diminuto/dwarf1 homolog;KIAA0018;Nbla03646;Seladin-1;SELADIN1;Selective AD indicator 1;Selective Alzheimer's Disease Indicator 1
UNIProt ID:
Q15392