DDAH1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16196-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16196-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16196-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16196-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DDAH1
Background:
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human DDAH1
Purification method:
Affinity purification
Target Synonym:
DDAH;DDAH I;DDAH-1;DDAH1;DDAH1;DDAHI;Dimethylargininase 1;Dimethylargininase-1;Dimethylarginine dimethylaminohydrolase 1;N(G);N(G)-dimethylarginine dimethylaminohydrolase 1;NG NG dimethylarginine dimethylaminohydrolase
UNIProt ID:
O94760