DCTN4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14938-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14938-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14938-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14938-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DCTN4
Background:
Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human DCTN4
Purification method:
Affinity purification
Target Synonym:
DCTN 4;Dctn4;DCTN4;Dynactin 4 (p62);Dynactin 4;Dynactin p62 subunit;Dynactin subunit 4;Dynactin subunit p62;Dynactin4;p62
UNIProt ID:
Q9UJW0