DCTN3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11144-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11144-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11144-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11144-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DCTN3
Background:
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant protein of human DCTN3
Purification method:
Affinity purification
Target Synonym:
DCNT22;DCTN 22;DCTN22;Dctn3;DCTN3;dynactin 3 (p22);dynactin 3;dynactin 3 isoform 1;Dynactin complex subunit 22 kDa subunit;dynactin light chain;Dynactin subunit 3;p22
UNIProt ID:
O75935