CK-6A/B/C Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22038-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22038-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22038-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22038-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:3B6
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Cytokeratin 6
Background:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
60kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-300, IF 1:100-1:300
Immunogen:
Synthetic Peptide
ObservedMW:
56-60kDa
Purification method:
Protein A purification
Target Synonym:
CK-6A;CK-6D;CK6A;CK6C;CK6D;Cytokeratin-6A;Cytokeratin-6D;K2C6A;K6A;K6C;K6D;keratin 6A;Keratin;Keratin;type II cytoskeletal 6A;Keratin-6A;Krt6a;KRT6C;KRT6D;type II cytoskeletal 6A;Type-II keratin Kb6
UNIProt ID:
P02538,P04259,P48668