CYP27A1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11121-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11121-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11121-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11121-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CYP27A1
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human CYP27A1
Purification method:
Affinity purification
Target Synonym:
12-alpha-triol 27-hydroxylase;5-beta-cholestane-3-alpha;5-beta-cholestane-3-alpha;7-alpha;12-alpha-triol 26-hydroxylase;5-beta-cholestane-3-alpha;7-alpha;12-alpha-triol 27-hydroxylase;5-beta-cholestane-3-alpha;7-alpha;12-alpha-triol 27-hydroxylase;7-alpha;Cholestanetriol 26 monooxygenase;CP27;CP27A;CTX;CYP;CYP27;CYP27A1;Cytochrome P 450C27/25;Cytochrome P-450C27/25;Cytochrome P450 27;Cytochrome P450 27 mitochondrial;Cytochrome P450 family 27 subfamily A member 1;Cytochrome P450 family 27 subfamily A polypeptide 1;Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1;mitochondrial;Sterol 26 hydroxylase;Sterol 26 hydroxylase mitochondrial;Sterol 26-hydroxylase;Sterol 27 hydroxylase;Sterol 27-hydroxylase;Vitamin D(3) 25 hydroxylase;Vitamin D(3) 25-hydroxylase
UNIProt ID:
Q02318