Cathepsin L Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10211-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10211-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10211-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10211-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CTSL
Background:
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human CTSL
Purification method:
Affinity purification
Target Synonym:
cathepsin L;1 b;Cathepsin L1;Cathepsin L1 light chain;CathepsinL;CATL;CATL1;cb15;CTSL;CTSL1;ctsl1b;FLJ31037;hgg1;Major excreted protein;MEP;MGC123162;wu:fb30g09
UNIProt ID:
P07711