Cathepsin E Polyclonal Antibody

Elabscience
Product Code: E-AB-10209
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10209-20uL20uL£125.00
Quantity:
E-AB-10209-60uL60uL£172.00
Quantity:
E-AB-10209-120uL120uL£237.00
Quantity:
E-AB-10209-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human stomach cancer and Mouse stomach tissue using Cathepsin E Polyclonal Antibody at dilution of 1:450
2 / 3
Immunohistochemistry of paraffin-embedded Human gastic cancer using Cathepsin E Polyclonal Antibody at dilution of 1:40
3 / 3
Immunohistochemistry of paraffin-embedded Human thyroid cancer using Cathepsin E Polyclonal Antibody at dilution of 1:40

Western Blot analysis of Human stomach cancer and Mouse stomach tissue using Cathepsin E Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human gastic cancer using Cathepsin E Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer using Cathepsin E Polyclonal Antibody at dilution of 1:40

Documents

Further Information

Abbreviation:
CTSE
Background:
The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
43kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CTSE
Purification method:
Affinity purification
Target Synonym:
CATE;CATE;Cathepsin E;Cathepsin E form II;CTSE;Erythrocyte membrane aspartic proteinase;Slow moving proteinase
UNIProt ID:
P14091