Cathepsin B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10208-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10208-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10208-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10208-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CTSB
Background:
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:150-1:500
Immunogen:
Recombinant protein of human CTSB
Purification method:
Affinity purification
Target Synonym:
Amyloid precursor protein secretase;APP secretase;APPS;CATB;Cathepsin B heavy chain;Cathepsin B1;CathepsinB;CPSB;CTSB;cysteine protease;OTTHUMP00000116009;OTTHUMP00000229510;OTTHUMP00000229511;OTTHUMP00000229512;OTTHUMP00000229514;OTTHUMP00000229515;OTTHUMP00000229516;Preprocathepsin B
UNIProt ID:
P07858