CTNNA1 Polyclonal Antibody

Elabscience
Product Code: E-AB-10207
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10207-20uL20uL£125.00
Quantity:
E-AB-10207-60uL60uL£172.00
Quantity:
E-AB-10207-120uL120uL£237.00
Quantity:
E-AB-10207-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of A431 cell using CTNNA1 Polyclonal Antibody at dilution of 1:600
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Immunohistochemistry of paraffin-embedded Human gastic cancer using CTNNA1 Polyclonal Antibody at dilution of 1:35

Western Blot analysis of A431 cell using CTNNA1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human gastic cancer using CTNNA1 Polyclonal Antibody at dilution of 1:35

Documents

Further Information

Abbreviation:
CTNNA1
Background:
Catenin alpha-1is aproteinthat in humans is encoded by theCTNNA1gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
100kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CTNNA1
Purification method:
Affinity purification
Target Synonym:
Alpha E-catenin;Cadherin associated protein 102kDa;Cadherin associated protein;Cadherin-associated protein;CAP 102;CAP102;Catenin (cadherin associated protein) alpha 1 102kDa;Catenin (cadherin associated protein);alpha 1;102kDa;Catenin alpha 1;Catenin alpha-1;CTNA1;CTNNA 1;Ctnna1;FLJ36832;FLJ52416;MDPT2;NY REN 13 antigen;OTTHUMP00000224141;OTTHUMP00000224147;Renal carcinoma antigen NY REN 13;Renal carcinoma antigen NY-REN-13
UNIProt ID:
P35221