COX4I1 Monoclonal Antibody
Code | Size | Price |
---|
E-AB-22002-20uL | 20uL | £125.00 |
Quantity:
E-AB-22002-60uL | 60uL | £172.00 |
Quantity:
E-AB-22002-120uL | 120uL | £237.00 |
Quantity:
E-AB-22002-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:2D4
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
COX IV
Background:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
20kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-3000, IHC 1:50-300, IF 1:100-1:300
Immunogen:
Recombinant Protein
ObservedMW:
15kDa
Purification method:
Protein A purification
Target Synonym:
AL024441;COX 4;COX IV 1;COX IV;COX IV-1;Cox4;COX41;Cox4a;COX4B;COX4I1;COX4I2;COX4L2;COXIV;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit 4 isoform 1 mitochondrial;Cytochrome c oxidase subunit 4 isoform 1;mitochondrial;Cytochrome C Oxidase subunit IV;Cytochrome c oxidase subunit IV isoform 1;Cytochrome c oxidase subunit IV isoform 2 (lung);Cytochrome c oxydase subunit 4;dJ857M17.2;MGC105470;MGC72016
UNIProt ID:
P13073
References
- https://www.tandfonline.com/doi/abs/10.1080/14756366.2020.1819257
- https://www.molbiolcell.org/doi/abs/10.1091/mbc.E18-12-0770