COMP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11095-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11095-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11095-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11095-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
COMP
Background:
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
83kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human COMP
Purification method:
Affinity purification
Target Synonym:
cartilage oligomeric matrix protein (pseudoachondroplasia;epiphyseal dysplasia 1;multiple);Cartilage oligomeric matrix protein;Cartilage oligomeric matrix protein precursor;COMP;COMP;EDM 1;EDM1;EPD 1;EPD1;Epiphyseal dysplasia 1;Epiphyseal dysplasia 1 multiple;Epiphyseal dysplasia multiple 1;MED;MGC13181;MGC149768;PSACH;pseudoachondroplasia (epiphyseal dysplasia 1;multiple);Pseudoachondroplasia;THBS 5;THBS5;Thrombospondin 5;Thrombospondin-5;Thrombospondin5;TSP5
UNIProt ID:
P49747
References
- https://www.mdpi.com/2076-2615/10/12/2420