Cleaved PARP1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22074-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22074-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22074-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22074-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:4A3
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Cleaved PARP
Background:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-3000
Immunogen:
Synthetic Peptide
ObservedMW:
116,89kDa
Purification method:
Protein A purification
Target Synonym:
ADP-ribosyltransferase diphtheria toxin-like 1;ADPRT 1;ADPRT;ADPRT1;APOPAIN;ARTD1;NAD(+) ADP-ribosyltransferase 1;PARP;PARP-1;PARP1;PARP1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;Poly[ADP-ribose] synthase 1;PPOL;SCA1
UNIProt ID:
P09874
References
- https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo01547h