Claudin 8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15676-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15676-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15676-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15676-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CLDN8
Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human CLDN8
Purification method:
Affinity purification
Target Synonym:
Claudin 8;Claudin-8;CLD8;Cldn8;Epididymis secretory protein Li 79;HEL S 79;OTTHUMP00000101915
UNIProt ID:
P56748