Claudin 1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15674-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15674-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15674-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15674-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CLDN1
Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
23kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:5000, IHC 1:100-1:300
Immunogen:
Synthetic peptide of human CLDN1
Purification method:
Affinity purification
Target Synonym:
Claudin-1;Claudin1;CLD 1;CLD1;CLD1;CLDN 1;Cldn1;ILVASC;SEMP 1;SEMP1;Senescence associated epithelial membrane protein 1;Senescence associated epithelial membrane protein;Senescence-associated epithelial membrane protein
UNIProt ID:
O95832
References
- https://www.sciencedirect.com/science/article/pii/S0899900720300757