CHRNA7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12583-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12583-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12583-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12583-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CHRFAM7A
Background:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
46kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human CHRFAM7A
Purification method:
Affinity purification
Target Synonym:
7nAChR;a7 nicotinic acetylcholine receptor;acetylcholine receptor;neuronal nicotinic;alpha-7 subunit;ACHA7;AChR;Acra7;alpha 7 neuronal nicotinic acetylcholine receptor;alpha-7 nicotinic cholinergic receptor subunit;alpha7;cholinergic receptor;neuronal nicotinic;alpha polypeptide 7;cholinergic receptor;nicotinic;alpha 7 (neuronal);cholinergic receptor;nicotinic;alpha 7;cholinergic receptor;nicotinic;alpha polypeptide 7;CHRNA7;CHRNA7-2;NACHRA7;neuronal acetylcholine receptor protein;alpha-7 chain;Neuronal acetylcholine receptor subunit alpha-7
UNIProt ID:
P36544