c-Fos Polyclonal Antibody

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Elabscience
Product Code: E-AB-30899
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-30899-20uL20uL£125.00
Quantity:
E-AB-30899-60uL60uL£172.00
Quantity:
E-AB-30899-120uL120uL£237.00
Quantity:
E-AB-30899-200uL200uL£344.00
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Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of 3T3, Hela cells using c-Fos Polyclonal Antibody at dilution of 1:1000.
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Western Blot analysis of 3T3, Hela cells using c-Fos Polyclonal Antibody at dilution of 1:1000.

Documents

Further Information

Abbreviation:
c-Fos
Background:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
41kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Immunogen:
Synthesized peptide derived from the N-terminal region of human c-Fos
ObservedMW:
62kDa
Purification method:
Affinity purification
Target Synonym:
Activator protein 1;AP 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog;FBJ Osteosarcoma Virus;FOS;FOS protein;FOS;G0 G1 switch regulatory protein 7;G0/G1 switch regulatory protein 7;G0S7;Oncogene FOS;p55;proto oncogene c Fos;Proto oncogene protein c fos;Proto-oncogene c-Fos;v fos FBJ murine osteosarcoma viral oncogene homolog
UNIProt ID:
P01100