CERS6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16562-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16562-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16562-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16562-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CERS6
Background:
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CERS6
Purification method:
Affinity purification
Target Synonym:
Ceramide synthase 6;CerS 6;CERS5;CerS6;LAG1 homolog ceramide synthase 6;LAG1 longevity assurance homolog 6;LASS 6;Lass6;LASS6;Longevity assurance homolog 6;MGC129949;MGC129950;T1L
UNIProt ID:
Q6ZMG9