CERS4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13375-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13375-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13375-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13375-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CERS4
Background:
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
46kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CERS4
Purification method:
Affinity purification
Target Synonym:
ceramide synthase 4;CerS4;FLJ12089;LAG1 homolog ceramide synthase 4;LAG1 longevity assurance homolog 4;LAG1;S. cerevisiae;homolog of;4;LASS 4;LASS4;LASS4 LAG1 homolog ceramide synthase 4;LASS4;TRAM homolog 1;Trh 1;Trh1
UNIProt ID:
Q9HA82