CERK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10955-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10955-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10955-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10955-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CERK
Background:
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human CERK
Purification method:
Affinity purification
Target Synonym:
Acylsphingosine kinase;Ceramide kinase;Cerk;CERK1;dA59H18.2;dA59H18.3;hCERK;KIAA1646;Lipid kinase 4;Lipid kinase LK4;LK4
UNIProt ID:
Q8TCT0