CDKN2AIP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10510-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10510-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10510-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10510-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CDKN2AIP
Background:
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human CDKN2AIP
Purification method:
Affinity purification
Target Synonym:
Calcium response factor;CARF;CARF;CDKN2A interacting protein;CDKN2A-interacting protein;Cdkn2aip;collaborates/cooperates with ARF (alternate reading frame) protein;Collaborator of ARF;FLJ20036
UNIProt ID:
Q9NXV6