VE-Cadherin Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12772-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12772-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12772-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12772-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CDH5
Background:
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CDH5
Purification method:
Affinity purification
Target Synonym:
7B 4;7B4;7B4 antigen;CADH5;Cadherin 5;Cadherin 5 type 2;Cadherin 5;type 2 (vascular endothelium);Cadherin 5;type 2;VE cadherin (vascular epithelium);cadherin;vascular endothelial;cadherin;vascular endothelial;1;Cadherin-5;Cadherin5;CD 144;CD144;CD144 antigen;CDH 5;CDH5;CDH5 protein;Endothelial specific cadherin;FLJ17376;OTTHUMP00000174777;Vascular endothelial cadherin;Vascular epithelium cadherin;VE Cad;VE-cadherin;VEC
UNIProt ID:
P33151