CDC25B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12785-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12785-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12785-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12785-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CDC25B
Background:
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CDC25B
Purification method:
Affinity purification
Target Synonym:
AI604853;Cdc 25B;Cdc25b;CDC25HU2;Cdc25m2;Cell division cycle 25 homolog B;Cell division cycle 25B;Cell division cycle 25B isoform 1;Cell division cycle 25B isoform 2;Cell division cycle 25B isoform 3;Cell division cycle 25B isoform 4;Cell division cycle 25B isoform 5;Dual specificity phosphatase Cdc25B;EC 3.1.3.48;M phase inducer phosphatase 2;M-phase inducer phosphatase 2;MPIP2
UNIProt ID:
P30305