CD68 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15981-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15981-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15981-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15981-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CD68
Background:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CD68
Purification method:
Affinity purification
Target Synonym:
CD 68;CD68;CD68 antigen;CD68 molecule;CD68;DKFZp686M18236;gp11;Gp110;LAMP4;Macrophage antigen CD68 (microsialin);MACROPHAGE ANTIGEN CD68;Macrosialin;SCARD1;Scavenger receptor class D member 1
UNIProt ID:
P34810