CD45 Monoclonal Antibody

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Elabscience
Product Code: E-AB-22009
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22009-20uL20uL£125.00
Quantity:
E-AB-22009-60uL60uL£172.00
Quantity:
E-AB-22009-120uL120uL£237.00
Quantity:
E-AB-22009-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:3H3
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Hela cells using CD45 Monoclonal Antibody at dilution of 1:2000.
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of Hela cells using CD45 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
CD45
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
147kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-300
Immunogen:
Synthetic Peptide
ObservedMW:
147kDa
Purification method:
Protein A purification
Target Synonym:
B220;CD 45;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;loc;Ly-5;LY5;Ly5;homolog of;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;Protein tyrosine phosphatase;receptor type C;protein tyrosine phosphatase;receptor type;C;Protein tyrosine phosphatase;receptor type;c polypeptide;Ptprc;PTPRC;Receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
UNIProt ID:
P08575