CD284 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-30816-20uL | 20uL | £125.00 |
Quantity:
| E-AB-30816-60uL | 60uL | £172.00 |
Quantity:
| E-AB-30816-120uL | 120uL | £237.00 |
Quantity:
| E-AB-30816-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CD284
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
96kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the Internal region of human CD284.
ObservedMW:
95kDa
Purification method:
Affinity purification
Target Synonym:
ARMD10;CD284;CD284 antigen;Homolog of Drosophila toll;hToll;TLR 4;TLR4;TLR4;TOLL;Toll like receptor 4;Toll-like receptor 4
UNIProt ID:
O00206