CD27 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14846-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14846-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14846-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14846-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CD27
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
29kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CD27
Purification method:
Affinity purification
Target Synonym:
CD 27;CD27;CD27 antigen;CD27 molecule;CD27;CD27L receptor;LPFS2;MGC20393;OTTHUMP00000238557;S152;T cell activation antigen CD27;T cell antivation antigen S152;T-cell activation antigen CD27;T14;TNFRSF 7;TNFRSF7;TNFSF7;Tp 55;Tp55;Tumor necrosis factor receptor superfamily member 7
UNIProt ID:
P26842