CD133 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-33462-20uL | 20uL | £125.00 |
Quantity:
| E-AB-33462-60uL | 60uL | £172.00 |
Quantity:
| E-AB-33462-120uL | 120uL | £237.00 |
Quantity:
| E-AB-33462-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CD133
Background:
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
97kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:20000
Immunogen:
Synthesized peptide derived from the N-terminal region of human CD133.
ObservedMW:
100kDa
Purification method:
Affinity purification
Target Synonym:
AC133;Antigen AC133;CD133;CORD12;Hematopoietic stem cell antigen;hProminin;MCDR2;MSTP061;OTTHUMP00000217744;OTTHUMP00000217745;OTTHUMP00000217746;PROM1;PROM1;Prominin I;Prominin like 1;Prominin like protein 1 precursor;Prominin mouse like 1;Prominin-1;Prominin-like protein 1;Prominin1;PROML1;RP41;STGD4
UNIProt ID:
O43490
References
- https://link.springer.com/article/10.1007/s12079-022-00692-0
- https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.0c00197