CCDC88A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13059-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13059-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13059-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13059-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CCDC88A
Background:
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CCDC88A
Purification method:
Affinity purification
Target Synonym:
AKT iphosphorylation enhancer;Akt phosphorylation enhancer;APE;Ccdc88a;Coiled coil domain containing 88A;Coiled coil domain containing protein 88A;Coiled-coil domain-containing protein 88A;FLJ10392;G alpha interacting vesicle associated protein;G alpha-interacting vesicle-associated protein;Galpha interacting vesicle associated protein;Girders of actin filament;Girdin;GIV;GRDN;GRDN;HkRP1;Hook related protein 1;Hook-related protein 1;KIAA1212
UNIProt ID:
Q3V6T2