CBR1 Polyclonal Antibody

Elabscience
Product Code: E-AB-10951
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10951-20uL20uL£125.00
Quantity:
E-AB-10951-60uL60uL£172.00
Quantity:
E-AB-10951-120uL120uL£237.00
Quantity:
E-AB-10951-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Mouse liver and Human fetal lung tissue, hela cell and Mouse kidney tissue, Human brain malignant glioma tissue using CBR1 Polyclonal Antibody at dilution of 1:900
2 / 3
Immunohistochemistry of paraffin-embedded Human breast cancer using CBR1 Polyclonal Antibody at dilution of 1:40
3 / 3
Immunohistochemistry of paraffin-embedded Human esophagus cancer using CBR1 Polyclonal Antibody at dilution of 1:40

Western Blot analysis of Mouse liver and Human fetal lung tissue, hela cell and Mouse kidney tissue, Human brain malignant glioma tissue using CBR1 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human breast cancer using CBR1 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human esophagus cancer using CBR1 Polyclonal Antibody at dilution of 1:40

Documents

Further Information

Abbreviation:
CBR1
Background:
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
30kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CBR1
Purification method:
Affinity purification
Target Synonym:
15 hydroxyprostaglandin dehydrogenase [NADP+];15-hydroxyprostaglandin dehydrogenase [NADP+];Carbonyl reductase [NADPH] 1;Carbonyl Reductase 1;CBR 1;CBR1;CBR1;CRN;NADPH dependent carbonyl reductase 1;NADPH-dependent carbonyl reductase 1;Prostaglandin 9 ketoreductase;Prostaglandin 9-ketoreductase;Prostaglandin E(2) 9 reductase;Prostaglandin-E(2) 9-reductase;SDR21C1
UNIProt ID:
P16152