CAV1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13048-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13048-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13048-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13048-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CAV1
Background:
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
20kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human CAV1
Purification method:
Affinity purification
Target Synonym:
BSCL3;CAV;CAV1;CAV1;caveolae protein;22 kD;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin-1;Caveolin1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;OTTHUMP00000025031;PPH3;VIP 21;VIP21
UNIProt ID:
Q03135