CAST Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14814-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14814-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14814-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14814-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CAST
Background:
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
77kDa
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human CAST
Purification method:
Affinity purification
Target Synonym:
BS 17;Calpain inhibitor;Calpastatin;Cast;Heart type calpastatin;ICAL;MGC9402;Sperm BS 17 component;Sperm BS-17 component
UNIProt ID:
P20810