CASP9 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-30760-20uL | 20uL | £125.00 |
Quantity:
| E-AB-30760-60uL | 60uL | £172.00 |
Quantity:
| E-AB-30760-120uL | 120uL | £237.00 |
Quantity:
| E-AB-30760-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Caspase-9
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
46kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen:
Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
APAF-3;APAF3;Apoptosis related cysteine peptidase;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;CASP-9;CASP9;CASP9;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1;regulatory subunit 56;RNCASP9
UNIProt ID:
P55211