CASP9 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22035-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22035-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22035-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22035-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:3I3
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Caspase 9
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
46kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Immunogen:
Synthetic Peptide
ObservedMW:
47-51kDa
Purification method:
Protein A purification
Target Synonym:
APAF-3;APAF3;Apoptosis related cysteine peptidase;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;CASP-9;CASP9;CASP9;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1;regulatory subunit 56;RNCASP9
UNIProt ID:
P55211
References
- https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo01547h