CASP2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10051-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10051-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10051-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10051-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CASP2
Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
51kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000
Immunogen:
Recombinant protein of human CASP2
Purification method:
Affinity purification
Target Synonym:
CASP 2;CASP-2;Casp2;CASP2;Caspase 2;Caspase 2 apoptosis related cysteine peptidase;Caspase-2 subunit p12;Caspase2;ICH 1;ICH 1 protease;ICH 1L;ICH1;ICH1 protease;ICH1L;NEDD-2;NEDD2;Neural precursor cell expressed developmentally down-regulated protein 2;PPP1R57;Protease ICH-1;Protein phosphatase 1 regulatory subunit 57
UNIProt ID:
P42575