CASP10 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13820-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13820-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13820-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13820-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
CASP10
Background:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human CASP10
Purification method:
Affinity purification
Target Synonym:
ALPS2;Apoptotic protease Mch-4;CASP 10;CASP-10;CASP10;CASPA;Caspase 10 apoptosis related cysteine peptidase;Caspase-10 subunit p12;FADD like ICE2;Fas associated death domain protein;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE 2;FLICE2;ICE like apoptotic protease 4;ICE-like apoptotic protease 4;Interleukin 1B converting enzyme 2;MCH 4
UNIProt ID:
Q92851