C12orf5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16101-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16101-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16101-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16101-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
C12orf5
Background:
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human C12orf5
Purification method:
Affinity purification
Target Synonym:
6-bisphosphatase TIGAR;C12ORF5;chromosome 12 open reading frame 5;FR2BP;Fructose-2;6-bisphosphatase TIGAR;Fructose-2;6-bisphosphate 2-phosphatase;Probable fructose 2;6 bisphosphatase TIGAR;Probable fructose-2;tigar;TIGAR;TP53 induced glycolysis and apoptosis regulator;TP53 induced glycolysis regulatory phosphatase;TP53-induced glycolysis and apoptosis regulator;Transactivated by NS3TP2 protein
UNIProt ID:
Q9NQ88