BABAM2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11008-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11008-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11008-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11008-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BRE
Background:
Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
44kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human BRE
Purification method:
Affinity purification
Target Synonym:
6030405P19Rik;AI429776;B830038C02Rik;Brain and reproductive organ expressed (TNFRSF1A modulator);brain and reproductive organ expressed protein;Brain and reproductive organ-expressed protein;BRCA1 A complex subunit BRE;BRCA1-A complex subunit BRE;BRCA1/BRCA2 containing complex subunit 4;BRCA1/BRCA2 containing complex subunit 45;BRCA1/BRCA2-containing complex subunit 45;BRCC4;BRCC45;bre;BRE
UNIProt ID:
Q9NXR7