BRAF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15531-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15531-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15531-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15531-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BRAF
Background:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
84kDa
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human BRAF
Purification method:
Affinity purification
Target Synonym:
FLJ95109;94 kDa B raf protein;B raf 1;B Raf proto oncogene serine threonine protein kinase;B Raf proto oncogene;serine/threonine kinase;B RAF1;B-Raf proto-oncogene serine/threonine-protein kinase (p94);BRAF 1;BRAF;BRAF;BRAF1;cRmil;MGC126806;MGC138284;Murine sarcoma viral (v-raf) oncogene homolog B1;Murine sarcoma viral v raf oncogene homolog B1;NS7;Oncogen BRAF;oncogene BRAF1;p94;Proto-oncogene B-Raf;Proto-oncogene c-Rmil;RAFB 1;RAFB1;RMIL;Serine/threonine-protein kinase B-raf;v raf murine sarcoma viral oncogene homolog B;v raf murine sarcoma viral oncogene homolog B1;v-Raf murine sarcoma viral oncogene homolog B1
UNIProt ID:
P15056