Amphiphysin II Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13951-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13951-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13951-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13951-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BIN1
Background:
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human BIN1
Purification method:
Affinity purification
Target Synonym:
AMPH 2;AMPH2;Amphiphysin 2;Amphiphysin II;Amphiphysin like protein;amphiphysin-like;Amphiphysin-like protein;AMPHL;Bin1;BIN1;Box Dependant MYC Interacting Protein 1;Box-dependent myc-interacting protein 1;Bridging integrator 1;DKFZp547F068;MGC10367;MGC105358;Myc box dependent interacting protein 1;Myc box-dependent-interacting protein 1;SH3P9
UNIProt ID:
O00499