BGLAP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16278-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16278-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16278-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16278-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BGLAP
Background:
Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human BGLAP
Purification method:
Affinity purification
Target Synonym:
BGLAP;BGP;Bone gamma carboxyglutamate (gla) protein;Bone gamma carboxyglutamate gla protein osteocalcin;Bone gamma carboxyglutamate protein;Bone Gla protein;Gamma carboxyglutamic acid containing protein;Gamma-carboxyglutamic acid-containing protein;OC;OCN;OSTCN;Osteocalcin;OTTHUMP00000016586;PMF1
UNIProt ID:
P02818