BDNF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12290-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12290-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12290-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12290-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BDNF
Background:
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150
Immunogen:
Synthetic peptide of human BDNF
Purification method:
Affinity purification
Target Synonym:
Abrineurin;ANON2;BDNF;BDNF;Brain Derived Neurotrophic Factor;Brain-derived neurotrophic factor;BULN2;MGC34632;Neurotrophin
UNIProt ID:
P23560