BCL2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15522-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15522-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15522-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15522-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BCL2
Background:
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
22kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human BCL2
Purification method:
Affinity purification
Target Synonym:
Apoptosis regulator Bcl 2;Apoptosis regulator Bcl-2;Apoptosis regulator Bcl2;AW986256;B cell CLL/lymphoma 2;B cell leukemia/lymphoma 2;Bcl-2;Bcl2;BCL2;C430015F12Rik;D630044D05Rik;D830018M01Rik;Leukemia/lymphoma;B-cell;2;Oncogene B-cell leukemia 2;PPP1R50;Protein phosphatase 1;regulatory subunit 50
UNIProt ID:
P10415
References
- https://www.sciencedirect.com/science/article/pii/S1043661822003930
- https://www.mdpi.com/1975256
- https://www.mdpi.com/1574002
- https://www.mdpi.com/1422-0067/22/15/8117
- https://www.spandidos-publications.com/10.3892/ijmm.2019.4432
- https://onlinelibrary.wiley.com/doi/abs/10.1002/mrd.23280
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773939/