BCL2 Monoclonal Antibody

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Elabscience
Product Code: E-AB-22004
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-22004-20uL20uL£125.00
Quantity:
E-AB-22004-60uL60uL£172.00
Quantity:
E-AB-22004-120uL120uL£237.00
Quantity:
E-AB-22004-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:1B3
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Hela cells using BCL2 Monoclonal Antibody at dilution of 1:1000.
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using BCL2 Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of Hela cells using BCL2 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BCL2 Monoclonal Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
Bcl-2
Background:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
26kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-2000, IHC 1:50-1:200
Immunogen:
Synthetic Peptide
ObservedMW:
26kDa
Purification method:
Protein A purification
Target Synonym:
Apoptosis regulator Bcl 2;Apoptosis regulator Bcl-2;Apoptosis regulator Bcl2;AW986256;B cell CLL/lymphoma 2;B cell leukemia/lymphoma 2;Bcl-2;Bcl2;BCL2;C430015F12Rik;D630044D05Rik;D830018M01Rik;Leukemia/lymphoma;B-cell;2;Oncogene B-cell leukemia 2;PPP1R50;Protein phosphatase 1;regulatory subunit 50
UNIProt ID:
P10415

References

  • https://www.sciencedirect.com/science/article/pii/S0753332220302663
  • https://link.springer.com/article/10.1007/s11356-023-25636-y
  • https://europepmc.org/article/pmc/pmc9204490?javascript_support=no
  • https://www.sciencedirect.com/science/article/pii/S0753332220310763
  • https://www.nature.com/articles/s41598-019-50679-y
  • https://www.frontiersin.org/articles/10.3389/fphys.2019.00132/full?report=reader
  • https://link.springer.com/article/10.1186/s12917-021-02951-5