BAX Polyclonal Antibody

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Elabscience
Product Code: E-AB-13814
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-13814-20uL20uL£125.00
Quantity:
E-AB-13814-60uL60uL£172.00
Quantity:
E-AB-13814-120uL120uL£237.00
Quantity:
E-AB-13814-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human brain malignant glioma tissue, MCF7, Raji and Lovo cell using BAX Polyclonal Antibody at dilution of 1:300
2 / 3
Immunohistochemistry of paraffin-embedded Human esophagus cancer using BAX Polyclonal Antibody at dilution of 1:30
3 / 3
Immunohistochemistry of paraffin-embedded Human lung cancer using BAX Polyclonal Antibody at dilution of 1:30
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Western Blot analysis of Human brain malignant glioma tissue, MCF7, Raji and Lovo cell using BAX Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human esophagus cancer using BAX Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human lung cancer using BAX Polyclonal Antibody at dilution of 1:30

Documents

Further Information

Abbreviation:
BAX
Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
21kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human BAX
Purification method:
Affinity purification
Target Synonym:
Apoptosis regulator BAX;BAX;Bax-protein;BAX;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl2-L-4;BCL2L4;membrane isoform alpha
UNIProt ID:
Q07812

References

  • https://www.mdpi.com/1806946
  • https://www.sciencedirect.com/science/article/pii/S0753332220302663
  • https://www.sciencedirect.com/science/article/pii/S0024320522002600
  • https://link.springer.com/content/pdf/10.1007/s13311-019-00803-7.pdf
  • https://link.springer.com/article/10.1186/s12902-022-01143-y
  • https://www.sciencedirect.com/science/article/pii/S0300483X18303937
  • https://link.springer.com/article/10.1007/s10895-023-03180-9
  • https://www.sciencedirect.com/science/article/pii/S0006291X19321874
  • https://link.springer.com/article/10.1007/s10123-018-00051-3
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106821/