BAK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10092-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10092-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10092-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10092-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
BAK1
Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
23kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human BAK1
Purification method:
Affinity purification
Target Synonym:
Apoptosis regulator BAK;BAK;BAK like;Bak NT;BAK;Bak1;Bcl 2 homologous antagonist/killer;Bcl 2 like 7 protein;Bcl-2 homologous antagonist/killer;Bcl-2-like protein 7;BCL2 antagonist/killer 1;Bcl2 like 7 Protein;Bcl2-L-7;BCL2L7;CDN1;Cell death inhibitor 1;MGC117255;MGC3887;NBak;Pro apoptotic protein BAK
UNIProt ID:
Q16611
References
- http://ar.iiarjournals.org/content/40/12/6723.short